SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d2dce334d7d4bf8e29aeae21cfa24e966336aab90ea3b9881d630e192df8668' 
  AND token = 'GieN//lbPgfBW044pLd1nq0Pfyl+VmOiUl27TphjBnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}