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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e050f22ba5205f6e9be0d67da5b48e2ca828f4df0ba75ace9d66e8c7dc61ab04' 
  AND token = 'fxri7tF0w72cFLS+rui9WWk0zZIjDuf3N1EsJlys8iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}