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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bb82cf07885fab1f9b542bfc8c839312d9d50f63a916d6dbc4733b88c968a9f' 
  AND token = 'uxXkKyY+wos3ymgfd86G0aj75u228jpV021uBv09Z98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}