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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fd5fba8fd306a6ee551845e28c2315bc4cd202f2ccbd84a960a028da3ae0cd4' 
  AND token = '4bwZxKOwCDocfsN4Dqz+fqRp25ML7LkT2OnBbj3aqxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}