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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0d3b7b791e962fd415b4f0461d2ff770b2884d92b5f7a0c4d4d1dda3c64270' 
  AND token = '3SxgE/JQIEAPPzbUvMqVR+3NrO7HmeM0uzEzPzm51a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}