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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae78e365d00ada74dee92ddb4ea0830d50312b26a9540b88b39e6fdd585f7438' 
  AND token = 'k1Pm3BLsl+3u//+0o6EUaBzrGCVN+10bObtnBJX7fzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}