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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5701f0fb38260a7828099769191d0b22156f20bda18379ca2c4754f925b93bde' 
  AND token = '4GJ4lj7LtIMXTA1p2uTJVA9D27OFAv8Y36XQ1BW3dL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}