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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caed247ba129cb49eb3caa2599e12f5e42a3d600cbc7aa0642700e79011b67aa' 
  AND token = 'QIComNiD0hS2JI5UZvE+ywgwOmV1KRVAgTPlQPWlHB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}