SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c57560961ba5fab0ddf8e97fddcceb8aa32d7e35a901f1a4311f38545af644b9' 
  AND token = 'jORScoQ4VvwGkcpdRg+9k0UUqst2YG81Bu5u6j3F4Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}