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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd9e9afdedf869ae5b1d92a0f7f6a3bc5b2c9e9d7a0a72a76e215a121365b226' 
  AND token = '6uEty4TBuFBdndIwK2U+89fiOB7xdB8zrnS2ftSCZTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}