SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4667e024f0b0f40b692dd8d7d3c839f6a6c1dfe8c483c754539f17de76b0084d' 
  AND token = 'QSd73u+mvVtQ1hnTr5PzJN18xqAoORhtxdCAX80YtTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}