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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f6c7cc82fb27334b62a961438e411de2a6e52d83fe1e9af6fdc0d75d878bce' 
  AND token = '4QEyU3/lS4oWFpCEI+EC3uQ4zecexL5d7fpNFZpnCN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}