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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4a7abd1c6b188fdc01981eebf5369bccc0fd832c0e5394ca5160d99014078df' 
  AND token = 'zKWMQE78R4NauUUDFgYGvLTr3sWI3/5/RgKB/X7wyB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}