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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9516a85d255c5a67a3f8b2345059474ee3cd4f37fdba99799dc484c99fe98f5c' 
  AND token = 'mlwxK9119MW333Kg2tAn42UZZ0x0/i0uOO6VPpPver8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}