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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7f326945e8fd9901eb4d832bc33b5e5bc2e00bc2eea740d6126d0b788c12d35' 
  AND token = 'CMECN4uxBBXCS9q41DwTyETAUjPk5plfSSjOIzF2Z8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}