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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e690c1b783e05058c48c1fee89f7370152b8ad31460c170ca1cc780ae5fcfa2d' 
  AND token = 'PTFX/+Pxu172pJUnY+p6yWqBB7kTjkcuN8y2wrtLwUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}