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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2980d68f304e9aa09a74bb08448ff8edf5b31d24b8d280a958e19a6302c2c61' 
  AND token = 'kA3vnktb4C5560+95+t0aIlKlio3oActvAro8xluMfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}