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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01cfa3020e38ed3b7a767ad4d9dacd470da7fcaa94485eed90ca613e2cb26901' 
  AND token = 'PBX4+XKAFwQC5h45ER3ysheN5hbIg3KcLZ3OMxmAu/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}