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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5235e43de60cefd5f2a43264bd6c60ee8638fc369af7deefcdff0f01fc92aa' 
  AND token = 'U06RZP2A7DrQsJvGpdoqa/0QW3hY3BqEq7uNl53JP1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}