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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9df96c49112bcf51d92c6334d4adadb7b54826a37e4588c85fce084e0f01ec9' 
  AND token = '+vq2+Fr/Vd9j0rjQXKqRs2a74MO9BcQGjWSw70kFolM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}