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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c5aaab20b6e184309e7c156a65f08c60507898b941f926eed8905d8b7d9a7b' 
  AND token = 'ALcDaBLlt1sYq+3xz086145EP3AYfVfnaZ8rfTfOzcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}