SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b095cba20de203f8051d769fd8922951005ebaf32b88e9c8cc59f8fb4a442e' 
  AND token = 'RyYsZkN6FoUR4ZjrbdqZQrondyKClinCngM3t/1pqQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}