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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46cc82bb7bbc83c4a26f933745acc75bcbed7d03373f1486a30d44b632721c0' 
  AND token = '6VFweRjuQVS/ysH8lU8GLWsYU+dnir0x0pBqEh3Ug7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}