SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86489d9508bb9d570169a1cf1d71b424b8e74419a7d6b7efb2e217d112d96bf1' 
  AND token = 'W46sEpSAz2q8wVc3xLIdA46cu/VKG6dO+ezrO25//Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}