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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c14224e98e08a263907fa78fd4c98204fc4b43bbe5b9bab6ec927b4cca462c2' 
  AND token = 'bU6k4OL76AEP3TN7fsMMBA9WRyurr21WbQTH7iWi91Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}