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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4883a4e846201cb88748584d41314fc80ba8aaf072baf0fd39e95cf7fd3d830f' 
  AND token = '718DDq4G2Tmetkg317DLWqwgSQDkTpcMdB71y3xDDA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}