SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea9be7f89defa11e85b79cf779a1022b92f0ab202c1d448949b2f40e804fba3f' 
  AND token = '14dC8gKeR4DKzb+YNVjetNjNAQ7UWAEs/YsABkqLasM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}