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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9073a50931d7821ca4dafa7a1eec101790f902d0c9d8f82fa9fc47e0e307b5f' 
  AND token = 'OWPAf8G8hMNFtPbMGUCaXcsVIxTk3OQ7+wCZn/2bB3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}