SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0207c0561246b17d9f72adb64bfadf63f56e0d9d7974190a431c5307309441' 
  AND token = '0FDNF9BIa7lX23wIb57b9L5Z1fTi+T4NZThM39o6adI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}