SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf6fde067620efc0ab74a400529df712bc10ad90fab04ed15c4332cb8336e224' 
  AND token = 'Bx0SUDJDfI/oO8EAppl3bk8cZpbJRRRe2+qIkC926P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}