SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41604a4460180aa63a34ee5c70f8df4cfa5c2d9ab2f6677454e96c06c12bba93' 
  AND token = 'FUCdk8TlRlXJiEMQL02WC/33iNaFHIwBzGu/ZUVqsTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}