SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05d73f0b9238981b0a6bf4d58f7d938cbb0e6dacbeacadbc9ad4ceab065e6380' 
  AND token = '5dqPfuIv+VoQKjqOEc4CWp1UfuC5RE00Ls4FJEyhz4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}