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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed18df2a910b0661a3fd44920e48cd4c77adff882279dc9139af8c1d92fb886f' 
  AND token = 'VlEuompqJiL3orgZxZHP18iZ7+kESJyjW9GB1Z4JcvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}