SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfbadfc0dd186cdcf03fdabb48d9fcac70abb748f8d5d7580a2ad21a61620180' 
  AND token = 'fvVun9osn0o8dBea7uHzkeHTRmsqc1UfBtBj4yHIGZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}