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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a780a5b1b3665f3d847be55202be46fdb852a88a428997daf8a8383cbf4333e' 
  AND token = 'SqSI7GrvX25nCF7h3ZNm3mTunlQXXg+y+z1A4lHf7Dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}