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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83961f854891c81a3b05cb738305e9d2bdff3211f1ad725951055d052809f6f8' 
  AND token = '+TzfsnJw0Nh80MMgT5AyyUcYG8g/yZeCUt6zcclFYBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}