SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8853fed76df82be681096962a0e2bd6781068ec79414fd5ff5084b2f7cd6490' 
  AND token = 'OdueC5x97bex89PaHQjizKXpcyrZHorr7uUktst150w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}