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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cb4dcd704d2ac3f6fd344ceb65fad6dc4cfc2a230340a505673fd337763714' 
  AND token = '9DK084Tvi5RemN1mRYj6p+0CI7fS1fM4Ca4UqqKSIOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}