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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e64772b4595de6689d63974a90e5a8c92889c2384c5a68da660039583394008' 
  AND token = 'sHcmAMa8UWQF1GeAe9HyAu9QAkNdPBgcTQBjsv7VvpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}