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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d1144816cac9b2e35be04af10c4875f51327fb1488a87de1aa4012076891e96' 
  AND token = 'XdM2UfQRazRuJOx/SgegrVfGEwUG4kGRXHLCxZoV/bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}