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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7822f7496b0ab0f3e67fb493478bd7f8d4dbc32bfa71ecc7c47055e3d6da9f18' 
  AND token = 'g3i4x41GYgSyPw0NzPpJ6RhlmXpmZXoT61yZtM0avxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}