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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c1e0650a087c9e1596e2164645c567698ec2bdc2a2a642f01a1080109e80a1' 
  AND token = 'twYh0Sy9dino4aZuPtLkKzs+cawm85+8Qq8juhQfmH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}