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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357b85f6a32d6d0f981d1dca1d2228de4f0fb9ad48ef95a775b457b1fca72d70' 
  AND token = 'b+1Fyft69Kif6/5wGAyy8fbnCiWHuzfLmjlaTySXVS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}