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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008da64e2e29437dda1e9b0c5b803632e11a55471aa11d1250cec68fb60549bc' 
  AND token = 'doq6uyfQYd8If4OWtm92YkEVFDi5XJy+XatThPaJGqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}