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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3253f4f2763e2da4d48d8dc439705bdbe1ad34353e4284c08977ceb59e37497c' 
  AND token = '1IMBcZ43WTiKO3KNCgFzFc8GBw/TXbU5hjvLs8Z585I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}