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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2671ff51376ea5bc96ac9be5f4bb70a930b499284e06bf29a10459494b0f02b3' 
  AND token = '4N1thCNipTDyPuC/4BSjmP9MyV/alVQFq0kaDRFZlUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}