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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ee424825c69b73272fcd19a13de2af51c7f766ee6f17b9d461b095679c38c6' 
  AND token = '0gE6EP/cdkE7YWUAjbu0jLxJHkuNjDKA43gMRDD07Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}