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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e90c3a4d25e381257f0d2b4e37f68081710fa807988495e4651a7e25cf08fa04' 
  AND token = 'bsq6SAs4+ZQxnJV9jBPTA1bX0fcOBRB9d2fvoiVuJGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}