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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21836a7f7cb5be6771e3858c25b232e697a77b7a7b8d39bf7571ab0310655de3' 
  AND token = '/hkJ4bGt2yiHV9WRb0WePYWtXeYFrxnPCpXUS7vsxw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}