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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25c76c7e947c5dd4e77905bb701f3696292952a64467b1f62dbc08a73412685' 
  AND token = '5Qkg9HsB56eHt5ifBsZbUI9rSc1CAUjPP/CD2VyFsfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}